Dr Shi, Jue Jade, Assistant Dean (Student Learning Experience) of the Faculty of Science and Associate Professor of the Department of Physics, has been selected for funding under the Research Grants Council (RGC) Research Fellow Scheme (RFS) 2021/22. Each RFS awardee will be conferred the title "RGC Research Fellow" and the supporting university will receive a fellowship grant of HK$5,155,380 over a period of 60 months.
Dr Shi has expertise in the interdisciplinary field of quantitative systems biology, which combines quantitative experimentation, in particular high-resolution live-cell imaging, with mathematical modeling to understand cell-cell interaction dynamics involved in anticancer drug response and immuno-oncology interactions. The research project that she leads in the RFS is entitled “Antitumor dynamics of Natural Killer cell and its Response to Immune Checkpoint Inhibitors in 3D Tumor Organoid Models”. The project will develop a new systemic framework that integrates multidisciplinary methodologies to quantitatively elucidate the antitumor dynamics of Natural Killer (NK) cells in 3D and uncover new insight into the molecular regulators underlying variable NK cell responses towards further developing NK cell-based cancer immunotherapy.
The RGC RFS aims to provide sustained support to exceptionally outstanding academics to facilitate their research and promote research excellence. In each round of the yearly exercise, only ten places will be offered under RFS. The ten RFS awardees were selected for their research capability, contribution and potential impact of the proposed research project, proven research track record, leadership quality and vision in the chosen area of research. Dr Shi has been selected out of the 32 nominations after a rigorous assessment process. She is also the first RFS awardee among the Faculty and the University. The award has recognized Dr Shi’s research ability and potential research impact.